Abstract

Abstract Summary: Protective Role of Metformin Against Microwave Radiation

Overview

The reproductive system is notably vulnerable to microwave radiation. This study explores the protective effects of metformin, an antidiabetic agent, against oxidative stress and damage induced by exposure to 2.856 GHz microwave radiation.

Findings

• Exposure to 2.856 GHz microwave radiation severely disrupts reproductive functions, highlighting a specific risk for the male reproductive system.
• Microwave radiation caused serum hormone disorders, decreased sperm motility, and affected sperm energy and testicular structure, alongside mitochondrial impairments.
• Metformin demonstrated significant protective effects, improving testicular structure and function by reducing oxidative damage and inhibiting apoptosis.

Conclusion

The application of metformin presents a promising avenue for mitigating the detrimental effects of microwave radiation on the reproductive health of male rats, providing insights into its potential use in clinical settings to shield reproductive health from electromagnetic hazards.