Abstract

Overview

The study investigates the potential adverse effects of 2.45 GHz microwave exposure, commonly emitted by Wi-Fi devices, on the cochlea in a controlled experimental setting using animal models.

Background

This research focuses on identifying low dose-dependent adverse responses of 2.45 GHz microwave radiation affecting the cochlea.

Methods

• Twelve pregnant female rats and their male newborns were subjected to different strengths of Wi-Fi frequencies during pregnancy and post-birth.
• Controlled exposures included electric field values ranging from 0.6 to 15 V/m.
• Auditory functions were assessed through auditory brainstem response testing pre and post-exposure.
• Histopathological evaluations were conducted using immunohistochemistry notably through caspase-3, -9, and TUNEL staining techniques.

Findings

Significant increases in auditory brainstem response thresholds were noted post-exposure at and above 5 V/m electric field strengths. Elevated levels of apoptosis indicators were most pronounced at higher dose exposures, demonstrating a direct correlation between electric field power and apoptotic activity within the cochlea.

Conclusion

The study conclusively shows that even at low electromagnetic field values, commonly found in Wi-Fi frequencies, there can be notable detrimental effects on the inner ear, predominantly through mechanisms of apoptosis and increased immune activity.