Effect of Electromagnetic Field Exposure on Mouse Brain Morphological and Histopathological Profiling
Abstract
Overview
Every day, devices like mobile phones expose brain tissue, located closest to these devices, to electromagnetic fields (EMF), possibly increasing the risk of neurological disorders. This study explored the effects of mobile phone EMFs on mice brain structures, focusing on both morphological and histopathological changes.
Introduction
- The study assesses the impact of EMFs from mobile phones on the brain tissues in mice.
- Reported frequencies were 1,350-1,375 MHz with specific absorption rates of 4.0 W/kg.
Material and Methods
The experiment used healthy BALB/c mice, divided into three groups of ten – one control and two exposed to different EMFs. Techniques utilized included brain segmentation and detailed histopathological analysis.
Findings
Exposure to EMFs resulted in significant morphological alterations such as:
- Shrinkage of pyramidal neurons.
- Mild perivascular and perineural oedema.
- Vacuolation in neurons and glial cells.
- Decrease in Purkinje cells and interstitial oedema in the cerebellum.
Conclusion
The proximity of mobile phones (3cm from the cage) caused noticeable changes in brain structures of mice, highlighting the urgent need for extensive research to establish safe exposure distances in both veterinary and biomedical fields.