Effect of Electromagnetic Field Exposure on Mouse Brain Morphological and Histopathological Profiling

Authors: Judita Zymantiene, Vida Juozaitiene, Rasa Zelvyte, Vaidas Oberauskas, Ugne Spancerniene, Antanas Sederevicius, Albina Aniuliene

Year: 2020 May 8

Category: Veterinary Science

Journal: J Vet Res

Institution: J Vet Res

DOI: 10.2478/jvetres-2020-0030

URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305646/

Abstract

Impact of EMF Exposure on Mouse Brain: An In-depth Study

Overview

Every day, devices like mobile phones expose brain tissue, located closest to these devices, to electromagnetic fields (EMF), possibly increasing the risk of neurological disorders. This study explored the effects of mobile phone EMFs on mice brain structures, focusing on both morphological and histopathological changes.

Introduction

  • The study assesses the impact of EMFs from mobile phones on the brain tissues in mice.
  • Reported frequencies were 1,350-1,375 MHz with specific absorption rates of 4.0 W/kg.

Material and Methods

The experiment used healthy BALB/c mice, divided into three groups of ten – one control and two exposed to different EMFs. Techniques utilized included brain segmentation and detailed histopathological analysis.

Findings

Exposure to EMFs resulted in significant morphological alterations such as:

  • Shrinkage of pyramidal neurons.
  • Mild perivascular and perineural oedema.
  • Vacuolation in neurons and glial cells.
  • Decrease in Purkinje cells and interstitial oedema in the cerebellum.

Conclusion

The proximity of mobile phones (3cm from the cage) caused noticeable changes in brain structures of mice, highlighting the urgent need for extensive research to establish safe exposure distances in both veterinary and biomedical fields.

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