Abstract

Overview

The impact of electromagnetic fields (EMFs) on biological entities has gained increased attention due to their prevalent use and potential health impacts. This study explores the biochemical and structural alterations in brain and liver tissues exposed to extremely low-frequency electromagnetic fields (ELF-MF).

Findings

• Study Setup: Utilizing a Merritt Coil System, a 500 μT 50 Hz ELF-MF was applied to animal samples, examining oxidative stress and chemical compositions via Raman spectroscopy and oxidative biomarkers.
• Changes in Biochemical Markers: Notable increases in malondialdehyde (MDA) and reductions in glutathione (GSH) indicate elevated oxidative stress.
• Raman Spectroscopic Analysis: Alterations in cerebral and hepatic tissues were noted, including:
  • Increased lipid peroxidation and decreased antioxidant responses.
  • Shift in amide III vibration peaks and lipid CH2 vibrations in brain tissues.
  • Heightened Raman intensities and structural lipid alterations in liver tissues.
• Multivariate Analyses: Principal component analysis (PCA) and hierarchical component analysis (HCA) effectively differentiated between the control and ELF-MF exposed groups.

Conclusion

The research indicates significant biochemical and structural changes in brain and liver tissues due to ELF-MF exposure, suggesting potential health risks associated with EMF exposure. These findings underscore the importance of continued research into the biological effects of EMFs.