Characterising core body temperature response of free-moving C57BL/6 mice to 1.95 GHz whole-body radiofrequency-electromagnetic fields

Authors: Sylvester E, Deng C, McIntosh R, Iskra S, Frankland J, McKenzie R, Croft RJ

Category: Bioelectromagnetics

Journal: Bioelectromagnetics

DOI: 10.1002/bem.22527

URL: https://onlinelibrary.wiley.com/doi/10.1002/bem.22527

Abstract

Overview

The present study investigates the core body temperature (CBT) responses in free-moving adult male and female C57BL/6 mice exposed to 1.95 GHz RF-EMF.

Methodology

  • Experiments conducted in custom-built reverberation chambers.
  • Temperature capsules implanted in intraperitoneal cavity.
  • Data continuously logged and transmitted postexposure via radiotelemetry.

Findings

Exposure levels ranged from 1.25 to 5 W/kg. A peak in CBT was noted in the first 16 minutes, statistically significant at ≥2.5 W/kg levels. The thermal effect largely dissipated during the remainder of the exposure

  • 1.25 W/kg: +0.15°C
  • 2.5 W/kg: +0.31°C
  • 3.75 W/kg: +0.24°C
  • 5 W/kg: +0.37°C

Conclusion

Mice seem to compensate effectively for the increased thermal load up to 5 W/kg. Notably, the elevated CBT at the end of the exposure was significantly reduced post-exposure, suggesting that immediate post-exposure measurements may not reflect true CBT changes due to RF-EMF.

electromagnetic fields core body temperature mice thermoregulation radiofrequency C57BL/6 SAR
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