Abstract

Overview

Recent studies have shed light on the effects of low-intensity radiofrequency (RF) fields on thermoregulation and adipose tissue metabolism.

Findings

• The study analyzed thermoregulatory gene expression and mitochondrial involvement in adipose tissue metabolism.
• Male C57BL/6J mice were exposed to RF fields at 900 MHz with specific absorption rates (SAR) of 0.1 W/kg or 0.4 W/kg for three or seven consecutive days.
• Findings indicated dose-dependent and time-dependent changes in adipose tissue markers.
• In brown adipose tissue (BAT), RF exposure reduced thermogenesis, decreased mitochondrial activity, but increased gene expression for balancing effects of reactive oxygen species (ROS).
• In white adipose tissue (WAT), RF exposure led to reduced fatty acid oxidation and impaired energy production, with no effects on mitochondrial biogenesis observed.

Conclusion

In conclusion, RF radiation exposure impacts adipose tissue by altering gene expressions linked to metabolism and thermogenesis in both BAT and WAT, with potential increases or decreases in thermogenesis and browning depending on exposure levels.