Abstract

Overview

With advances in technology, the emission of radiofrequency radiation (RFR) from mobile devices has raised concerns about potential health implications. This study examines the impact of 2100 MHz RFR on the testicular health of rats, focusing on TAM receptors and their ligands, which are key for spermatogenesis and testosterone production.

Findings

• Control and sham-exposed groups maintained normal testicular morphology, while RFR-exposed groups showed disrupted processes of spermatogenesis.
• The expression of TAM receptors (Tyro 3, Axl, Mer) did not significantly differ among the groups, although Tyro 3 was increased in Sertoli cells upon RFR exposure.
• Increased apoptotic indicators in exposed groups suggest that RFR may interrupt TAM signaling, leading to cell accumulation and potential infection.

Conclusion

The study indicates that RFR exposure could impair rat testicular function and morphology, although the exact effects on testicular function require further investigation. The results highlight the importance of assessing RFR's reproductive toxicity, especially in the context of increasing daily exposure from cell phones.