Effect of electromagnetic radiation on the liver structure and ultrastructure of in utero irradiated rats

Abstract

Overview

The study aimed to explore the effects of electromagnetic radiation (EMR) on the liver's structure and ultrastructure in rats exposed in utero.

Methodology

Pregnant rats were exposed to pulsed microwave radiation with a frequency of 2.45 GHz and a mean power density of 2.8 mW/cm2 daily for 2 hours throughout their pregnancy. Post-delivery, the offspring was not subjected to further EMR exposure.

Findings

• Light and transmission electron microscopy were employed to evaluate histopathological changes in the liver of 5-week-old offspring.
• The fundamental structure of the liver, including the size and shape of liver lobuli and connective tissue levels, showed no significant alterations.
• Mild structural changes were observed at the cellular level, such as altered microvilli shape and quantity, vesicle formation, and differences in endothelial cell fenestrations.

Conclusion

Although the changes were mild, they underline the subtle influence of EMR on liver ultrastructure. This prompts a need for further research to fully ascertain the impacts and potential risks of EMR exposure during pregnancy, highlighting the importance of precaution when evaluating EMR safety for developing organisms.