Abstract

Overview

This study examines the effect of 1.8 GHz radiofrequency electromagnetic field (RF-EMF) on genetic stress parameters in rat brain tissues, focusing on the activation of certain stress-related protein pathways.

Methodology

• Subjects: 27 mature female Wistar albino rats.
• Exposure: Rats were exposed to 1.8 GHz RF-EMF for 2 hours a day over 8 weeks.
• Dosage: The Specific Absorption Rate (SAR) was maintained at 0.06 W/kg.

Key Findings

The study found significant changes in p38MAPK gene expression, associated with cellular stress responses, specifically upregulated in rats exposed to RF-EMF. No significant changes were noted for Hsp27 gene expression.

Conclusion

Continuous exposure to 1.8 GHz cellular phone radiation can activate the Hsp27/p38MAPK stress pathway, potentially leading to cellular disorders and influencing brain function.