Liver tissues oxidative status, epigenetic and molecular characteristics in rats administered magnetic and microwave treated water

Authors: Elmoslemany AM, Ghamry HI, Awad AA, El-Kholy RI, Almami ISM, Alyamani NM, Zedan AMG

Year: 2023 Mar 16

Category: Biomedical Research

Journal: Sci Rep

DOI: 10.1038/s41598-023-31168-9

URL: https://www.nature.com/articles/s41598-023-31168-9

Abstract

Overview

This study investigates the impact of magnetized and microwave-treated water on the liver tissues of albino rats.

Findings

  • Three groups of rats were tested: one with tap water, one with magnetized water, and one with microwave-treated water.
  • Microwave-treated water cause a significant increase in liver enzymes and bilirubin levels, indicating stress and potential damage to liver tissues.
  • Oxidative stress markers increased and antioxidant parameters decreased significantly in rats given microwave-water.
  • Molecular analysis showed down-regulation of Metallothionein and CYP genes in magnetized-water administered rats compared to tap-water, and similar downregulation plus changes in Amylase and HDAC3 genes in microwave-water administered rats.

Conclusion

Microwave-treated water induced significant oxidative, molecular, and histopathological changes in liver tissues, suggesting a clear health risk. Conversely, magnetized water from higher magnetic power showed no adverse effects on the liver, providing a safer alternative.

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