Abstract

Oxidative Stress and Energy Metabolism in Male Reproductive Damage

Overview

The study explores the effects of high-power microwave (HPM) exposure at frequencies 1.5GHz and 4.3GHz on male reproductive systems using male Wistar rats. These investigations look into the impacts on testicular structures and overall sperm health under different exposure scenarios.

Findings

• Exposure to 1.5GHz and 4.3GHz individually caused significant damage to testicular tissues and reduced sperm quality.
• Similar levels of damage were observed in both single and combined exposure scenarios.
• Significant changes were noted in histological and ultrastructural levels with a decrease in sperm viability and motility.
• Serum testosterone levels and other reproductive hormones showed initial decrease but partially recovered by day 14 post-exposure.
• Decreased activities in key enzymes involved in energy metabolism and increased oxidative stress markers were recorded.

Conclusion

The study concludes that both single and combined exposures to L-band and C-band high-power microwaves adversely affect male reproductive systems, with oxidative stress and disturbances in energy metabolism being central to the mechanism of damage.