Mobile Phone (1800MHz) Radiation Impairs Female Reproduction in Mice, Mus musculus, through Stress Induced Inhibition of Ovarian and Uterine Activity

Abstract

Overview

The present study explores the extensive impact of mobile phone radiation at 1800MHz on the female reproductive capabilities in mice. Specifically, it assesses how different phone operation modes (stand-by, dialing, and receiving) affect ovarian and uterine structures and their hormonal functionalities.

Findings

• Exposure to mobile phone radiation was associated with increased levels of reactive oxygen species (ROS), nitrogen oxide (NO), lipid peroxidation, and total carbonyl content.
• Elevated serum corticosterone and decreased activity of antioxidant enzymes were noted in the hypothalamus, ovary, and uterus.
• A notable decline in the number of developing follicles, mature follicles, and corpus lutea in exposed mice compared to controls.
• Significant reductions were observed in serum levels of pituitary gonadotrophins (LH, FSH), sex steroids (E2 and P4), and expressions of key steroidogenic proteins and receptors, indicating impaired reproductive hormone function.

Conclusion

The study indicates that exposure to mobile phone radiation can induce oxidative and nitrosative stress and disrupt the reproductive functions in female mice, emphasizing the potential risks of cellular phone usage on female reproductive health.