Histopathologic effects of mobile phone radiation exposure on the testes and sperm parameters: a systematic literature review of animal studies

Abstract

Overview

The study investigates the histopathological changes in the testes and effects on sperm parameters following exposure to mobile phone radiation in experimental animals, highlighting concerns about male infertility linked to electromagnetic radiation from mobile devices.

Introduction

Male infertility issues, often stemming from suboptimal production of healthy, active sperm, may be worsened by mobile phone radiation. This radiation notably disrupts spermatogenesis, leading to declines in sperm quality and affecting major cellular components of the testes such as Leydig cells and seminiferous tubules.

Methods

• Extensive literature search in databases including PubMed, ScienceDirect, Hinari, and Google scholar.
• Screening of 752 studies, where 18 were selected for data extraction.

Results

• Significant histopathological changes were observed in cellular structures of the testes, such as decreased seminiferous tubule diameter and germinal epithelial thickness, alongside Leydig cell hypoplasia.
• Adverse effects on sperm parameters like decreased sperm count, motility, and viability, and increased abnormal sperm morphology were also reported in male rats, mice, and rabbits.

Conclusion

The research consolidates evidence that mobile phone radiation could detrimentally affect both the testicular structure and sperm function in animals, potentially extending to human reproductive health risks. Preventive steps are advised to mitigate this potential risk, with the call for more thorough research to explore these effects further.