The protective effects of melatonin against electromagnetic waves of cell phones in animal models: A systematic review

Authors: Amiri M, Khazaie H, Mohammadi M.

Year: 2025 Feb 24

Category: Systematic Review

Journal: Animal Model Exp Med

DOI: 10.1002/ame2.12552

URL: https://onlinelibrary.wiley.com/doi/10.1002/ame2.12552

Abstract

Overview

The increasing use of cell phones has spurred research into the adverse effects of electromagnetic radiation on human health aspects such as neuropsychological and reproductive systems. The most identified cause of these effects is oxidative stress. This systematic review aims to examine the role of melatonin in protecting against these radiations in various organs.

Methods

  • Analysis of selected articles from databases like Google Scholar, PubMed, Embase, Scopus, Web of Science, and Science Direct.
  • Focus on research using keywords 'melatonin', 'cell phone radiation', and 'animal model'.
  • Application of PRISMA guidelines and JBI checklist for quality assessment.

Findings

This review covered 11 articles of validated quality, which explored the antioxidative roles of melatonin in organs such as the brain, skin, eyes, testis, and kidneys affected by electromagnetic radiation. Results showed significant protection by melatonin against tissue atrophy and cell death induced by electromagnetic waves.

Conclusion

The review supports the protective effects of melatonin against electromagnetic waves in animal models. It suggests further research, particularly into melatonin’s potential as a preventive treatment for electromagnetic wave-induced damage in humans and its optimal administration.

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