High-Power Electromagnetic Pulse Exposure (EMP) of Healthy Mice: Effects on Cognition, Neuronal Activity, and Hippocampal Structures

Authors: Hao Y, Liu W, Xu Z, Jin X, Ye Y, Yu C, Hu C, Zuo H, Li Y

Year: 2022 Jun 29

Category: Neuroscience

Journal: Front Cell Neurosci

DOI: 10.3389/fncel.2022.898164

URL: https://www.frontiersin.org/articles/10.3389/fncel.2022.898164/full

Abstract

Overview

Electromagnetic pulse (EMP) exposure has been subject to study for its effects on biological organisms, particularly focusing on its influence on the brain. The brain’s sensitivity to electromagnetic radiation requires careful examination of EMP’s biological impacts and their mechanisms.

Findings

  • The study aimed to observe the effects of high-intensity EMP on mice cognition and neuronal activities.
  • A specific animal model used male C57BL/6N mice exposed to 300 kV/m EMPs.
  • Behavioral experiments gauged impacts on spatial and avoidance learning and memory, novelty-seeking, and anxiety.
  • In vivo measurements were recorded during and after EMP exposure, showing decreased spatial memory and altered neuronal activities in the hippocampal CA1 area.
  • Structural neuron damages in the hippocampi were documented through microscopy post-exposure.

Conclusion

Exposure to high-power EMP significantly impacts spatial learning and memory and disrupts normal neuronal activities, underlying potential health risks from electromagnetic fields. Structural damage to hippocampal neurons suggests lasting effects and necessitates further investigation into EMP safety protocols.

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