Abstract

Overview

Epidemiological studies have highlighted a potential link between exposure to extremely low-frequency magnetic fields (ELF-MF) and the increased risk of nervous system diseases.

Findings

• The study focused on the impact of 50 Hz magnetic field exposure, set at 2.0 mT over periods up to 24 hours, on DNA integrity and cellular functions across various neurogenic cell lines and primary cultured cells.
• Assessment included DNA damage via γH2AX foci formation, cell cycle effects, cell viability, cytokine secretion, and phagocytic activity in microglia, alongside various neuronal development markers.
• No significant changes were observed in the early marker of DNA double-strand breaks, cytokine secretion, cell cycle progression, or the phagocytic activity.

Conclusion

Despite no observed immediate DNA or cellular dysfunction in the exposure setting described, the study supports the need for continuous monitoring due to the established epidemiological associations suggesting possible long-term effects on nervous system health.