Abstract

Abstract Summary

Overview

Glioblastoma (GBM) is recognized as the most common and aggressive type of brain tumor, often resulting in significant disability and reduced survival rates. The origins of this cancer remain largely unclear, and there is ongoing research into potential risk factors, focusing on those that are modifiable.

Findings

• The study reviewed a total of 12 earlier research works, including both case-control and cohort studies.
• Factors such as body mass index (BMI), alcohol consumption, and the use of NSAIDs showed a potential protective effect against GBM.
• No significant correlation was found between GBM and exposure to magnetic fields according to this systematic review. However, individual studies within the analysis provide conflicting results, with one indicating a higher GBM risk with increased exposure to magnetic fields.

Limitations

The main limitation cited in the review is the relatively small sample size of studies included, which limits the robustness of conclusions that can be drawn. It points out that variations in how exposures were defined and measured across studies, and reliance on self-reporting, can introduce recall bias, especially since GBM can impact memory.

Conclusion

While certain lifestyle factors may influence GBM risk, the evidence does not strongly link magnetic field exposure to increased incidence rates of GBM. More comprehensive and well-followed-up studies are required to provide clearer insights.