Abstract

Abstract Summary

Overview

This global study evaluates the incidence, mortality, risk factors, and trends of central nervous system (CNS) cancer, detailing variations by sex, age, and country using comprehensive registry data.

Methods

• Extraction of CNS cancer incidence and mortality rates from multiple prominent databases including GLOBOCAN (2020), WHO mortality database, and others.
• Analysis of trends through Average Annual Percentage Change (AAPC) using Joinpoint regression.
• Assessment of risk factors like Human Development Index, GDP per capita, and mobile phone use.

Findings

• Global age-standardized rates for CNS cancer: 3.5 incidence and 2.8 mortality per 100,000 people.
• Regions with the highest rates: Southern Europe and Western Asia.
• Evidence linking mobile phone use and other risk factors to increased CNS cancer incidence, particularly in the younger male population in certain countries.

Conclusion

Overall, global CNS cancer trends are stable but highlight urgent areas for additional study, particularly due to increasing trends in young males and associations with electromagnetic field exposure from mobile phones. This raises significant health concerns and underscores the need for caution and further research into the impact of electromagnetic fields on health.