Disease Burden, Risk Factors, and Trends of Primary Central Nervous System (CNS) Cancer: a global study of registries data
Abstract
Global Central Nervous System Cancer Study - An Analysis
Overview
This research provides a comprehensive evaluation of the global incidence, mortality, and risk factors related to central nervous system (CNS) cancers, considering variations across sexes, age groups, and countries.
Methods
- Data on CNS cancer incidence and mortality was sourced from multiple authoritative databases including the GLOBOCAN 2020, WHO, and others.
- The study utilized regression analysis to track trends over time and examine factors associated with incidence and mortality rates.
Findings
The study highlights notable geographical variances with the highest age-standardized rates observed in Southern Europe and Western Asia. Other significant associations included economic indicators and lifestyle factors such as mobile phone use.
- Incidence of CNS cancer was associated with higher human development indexes and gross domestic product per capita.
- Considerable concerns were raised regarding increased incidences in younger males in specific regions.
Conclusion
Despite a global stability in CNS cancer trends, escalating cases in sub-populations signal potential underlying shifts in risk factors. The associations with socioeconomic factors and mobile phone use necessitate ongoing monitoring and research, reflecting potential EMF risks. The upward trend in younger males particularly underscores an urgent need for targeted investigations to understand and mitigate these risks.