Effects of Nonthermal Radiofrequency Stimulation on Neuronal Activity and Neural Circuit in Mice
Abstract
Overview
Research examines the effects of nonthermal radiofrequency radiation (RFR) on the nervous system using a mouse model.
Findings
- Animal model used showed spatial memory impairment by exposure to 2856-MHz RFR at levels comparable to thermal noise (≤1 °C).
- Glutamate release in the dorsal hippocampus CA1 region remains consistent post-exposure. Nevertheless, a notable reduction in dopamine release occurs.
- Enhanced calcium activity in CA1 pyramidal neurons via nonthermal mechanisms, returning to base levels with the cessation of RFR exposure.
- The reduced dopaminergic projection density from the locus coeruleus to the dorsal hippocampus underpins suppressed dopamine release.
Conclusion
Nonthermal RFR significantly alters neuronal activity, impacting neural circuits and potentially affecting nervous system functionality.