Effects of Long-Term and Multigeneration Exposure of Caenorhabditis elegans to 9.4 GHz Microwaves

Abstract

Overview

This study investigates the long-term and multigenerational effects of 9.4 GHz microwave exposure on Caenorhabditis elegans (C. elegans), an alternative model organism to the more frequently used rodents and cells.

Study Design and Exposure

Wild-type N2 strains of C. elegans were exposed to 9.4 GHz microwaves at a specific absorption rate of 4 W/kg for 10 hours daily. This exposure spanned from the L1 larval stage to adulthood and continued through 20 generations.

Findings

• Fecundity: A significant decrease in fecundity was observed in the exposed groups starting from the 15th generation.
• Growth and Mobility: Notable decreases in growth and motility were reported in the 10th generation of exposed worms.
• Oxidative Stress: Signs of oxidative stress appeared from the 10th generation onwards, which is hypothesized to interfere with normal spawning.

Conclusion

The study provides initial evidence that long-term exposure to microwaves can cause biological effects such as oxidative stress leading to decreased spawning in C. elegans. These findings underscore the need for further research to elucidate the underlying mechanisms.