0.263 terahertz irradiation induced genes expression changes in Caenorhabditis elegans (roundworm)

Authors: Shang S, Gao F, Zhang Q, Song T, Wang W, Liu D, Gong Y, Lu X

Year: 2024 Mar 2

Category: Genetics

Journal: iScience

DOI: 10.1016/j.isci.2024.109391

URL: https://www.cell.com/iscience/fulltext/S2589-0042(24)00612-6

Abstract

Overview

The study explores the biosafety concerns surrounding terahertz (THz) waves, particularly with their increasing application. Utilizing Caenorhabditis elegans, the research aims to uncover the biological impacts of 0.263 THz irradiation exposure.

Findings

  • Integration of transcriptome sequencing and behavioral tests revealed epidermal ultrastructure damage.
  • Expression of cuticle collagen genes was inhibited, affecting worm mobility.
  • Significant down-regulation in genes related to the immune and neural systems was observed.

Conclusion

The study provides new insights into the biological consequences of high-power THz radiation, highlighting potential systemic responses and epidermal damage in Caenorhabditis elegans.

terahertz irradiation Caenorhabditis elegans transcriptome sequencing biological effects epidermal damage gene expression
← Back to Stats