0.263 terahertz irradiation induced genes expression changes in Caenorhabditis elegans (roundworm)

Authors: Shang S, Gao F, Zhang Q, Song T, Wang W, Liu D, Gong Y, Lu X

Year: 2024 Mar 2

Category: Molecular Biology

Journal: iScience

DOI: 10.1016/j.isci.2024.109391

URL: https://www.cell.com/iscience/fulltext/S2589-0042(24)00612-6

Abstract

Overview

The biosafety of terahertz (THz) waves has emerged as a new area of concern with the gradual application of terahertz radiation. Even though many studies have been conducted to investigate the influence of THz radiation on living organisms, the biological effects of terahertz waves have not yet been fully revealed.

Key Findings

  • In this study, Caenorhabditis elegans (C. elegans) was used to evaluate the biological consequences of whole-body exposure to 0.263 THz irradiation.
  • Integration of transcriptome sequencing and behavioral tests revealed:
    • High-power THz irradiation damaged the epidermal ultrastructures
    • Inhibition of the expression of the cuticle collagen genes
    • Impairment of the movement of C. elegans
    • Genes involved in the immune system and neural system were dramatically down-regulated by high-power THz irradiation

Conclusion

Our findings offer fresh perspectives on the biological impacts of high-power THz radiation that could cause epidermal damage and provoke a systemic response.

🔎 EMF Safety Relevance: This study strongly suggests there are molecular and behavioral effects of terahertz radiation, including impairment in key physiological systems, highlighting the urgent need for safety evaluations regarding THz exposure.

terahertz radiation gene expression Caenorhabditis elegans biosafety neural system immune response epidermal damage
← Back to Stats