Simulated mobile communication frequencies (3.5 GHz) emitted by a signal generator affects the sleep of Drosophila melanogaster

Authors: Yahong Wang, Hongying Zhang, Ziyan Zhang, Boqun Sun, Chao Tang, Lu Zhang, Zhihao Jiang, Bo Ding, Yanyan Liao, Peng Cai

Year: 2021 Apr 5

Category: Environmental Pollution

Journal: Environ Pollut

DOI: 10.1016/j.envpol.2021.117087

URL: https://pubmed.ncbi.nlm.nih.gov/33894629/

Abstract

Overview

With the ongoing advancements in technology, particularly the imminent deployment of 5G, concerns regarding the biosafety of radiofrequency radiation (RF-EMR) on health are increasingly pertinent. This study utilizes Drosophila melanogaster to assess the effects of 3.5 GHz RF-EMR, emblematic of 5G frequencies.

Method and Findings

  • Experimental Setup: A 3.5 GHz RF-EMR environment was recreated at multiple intensities (0.1, 1, and 10 W/m2).
  • Observational Data: Both short-term and long-term exposures were analyzed for their impact on activity levels and sleep patterns in male flies, both parental and first-generation (F1).
  • Genetic and Neurochemical Analysis: Core genes related to heat stress and the circadian clock were analyzed along with neurotransmitters using QRT-PCR and UPLC-MS technologies.

Results

Short-term exposure increased activity and decreased sleep, whereas long-term exposure showed an inverse effect, reducing activity and increasing sleep. Notable findings include heightened expression of heat stress response genes and changes in circadian clock genes under long-term exposure scenarios. Levels of neurotransmitters like GABA and glutamate were also altered.

Conclusion

This comprehensive study demonstrates the varied neurological and genetic impacts of long-term exposure to RF-EMR on Drosophila melanogaster, highlighting potential health risks associated with prolonged 5G RF exposure. The results contribute valuable insights into the complex biological impact of emerging technologies.

5G RF-EMR Drosophila melanogaster biosafety neurobiology
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