Possible effects of different doses of 2.1 GHz electromagnetic radiation on learning, and hippocampal levels of cholinergic biomarkers in Wistar rats
Abstract
Overview
The study investigates the impact of short-term exposure to 2.1 GHz radiofrequency electromagnetic radiation (RF-EMR) at different doses on rat behavior and hippocampal biomarkers.
Methodology
- Rats divided into three groups: one sham-exposed, two exposed to 45 V/m and 65 V/m doses respectively for one week.
- Behavioral assessments done using object location and Y-maze tasks.
- Hippocampal biomarkers such as AChE, ChAT, and VAChT tested via Western Blotting and Real-Time PCR.
Findings
Significant impairments in behavioral tasks and lower levels of hippocampal cholinergic biomarkers were noted particularly in rats exposed to 65 V/m, suggesting a dose-dependent effect.
Conclusion
The results indicate a potential risk of short-term exposure to 2.1 GHz RF-EMR to cognitive functions and neural biochemistry in rats, highlighting the need for further research on the influence of RF-EMR on the central cholinergic system.