Abstract

Overview

The paper discusses comprehensive research on the impact of terahertz (THz) electromagnetic radiation across a frequency range of 0.5-100 THz, analyzing various power densities and exposure times on both normal and cancer cells. It also explores the use of spectroscopic methods in the THz range and the utilization of interstitial water spectra as a diagnostic tool for pathological conditions.

Effects on Cellular Structures

The study identifies multiple effects of THz radiation on cellular components, notably:

• Alterations to cell membrane properties
• Formation of pores and activation of ion channels
• Impact on cellular proliferation and viability

Mechanisms of Action

Possible mechanisms influencing cellular response to THz radiation include:

• Conformation changes in membrane proteins affecting intracellular signaling
• Charge redistribution on cell membranes
• Excitation of resonant oscillations affecting macromolecular structures

Conclusion

The study concludes that while THz radiation affects vibrational-rotational movements of biological molecules and does not break covalent bonds, it plays a significant role in altering protein and cellular interactions. Despite no consensus on the damaging effects of THz radiation, its potential in non-thermal medical applications, particularly in oncology, is recognized.