Abstract

Abstract

Overview

In a number of recently published experimental studies from our research group, the positive impact of magnetic stimuli (static/pulsed) on cell functionality modulation or bactericidal effects, in vitro, has been established.

Study Objectives and Methodology

The study aims to develop a theoretical understanding of magnetobiological effects. It presents two quantitative models that determine magnetic Maxwell stresses and pressure on the cell membrane under the influence of a time varying magnetic field.

Findings

• The predicted magnetic field-induced stress on cell/bacteria depends on the conductivity properties of the extracellular region, which are insufficient to cause significant effects.
• Conversely, the force due to the induced electric field is found to be more influential, impacting membrane tension and potentially causing membrane poration.

Conclusion

With known critical membrane tensions for cells, parameters for field-induced membrane rupture are estimated. This classifies the magnetic field effects into three regimes: no effect, biophysical stimulation, or cell death due to membrane damage. This work offers valuable quantitative insights into the interactions between magnetic fields and biological systems.