Zinc affects nuclear factor kappa b and DNA methyltransferase activity in C3H cancer fibroblast cells induced by a 2100 MHz electromagnetic field
Abstract
Overview
The proliferation of mobile phone usage highlights the growing concern regarding the effects of electromagnetic fields (EMF) on human health. This study analyzes the adverse effects of EMF emitted by mobile devices.
Findings
- Investigation focused on the impact of zinc on C3H cancer fibroblast cells exposed to 2100 MHz EMF.
- Cell groups: Control, sham control, 2100 MHz EMF, combinations of 50, 100, and 200 µM Zinc + 2100 MHz EMF for 2 hours.
- Increased cell viability was observed in the EMF exposure group, yet subsequent decrease in viability with zinc treatments.
- Significant escalation in Nuclear Factor Kappa B (NF-κB) and DNA Methyltransferase (DNMT) activities due to 2100 MHz EMF exposure, which was mitigated by zinc supplementation.
Conclusion
This study illustrates that 2100 MHz EMF exposure augments NF-κB and DNMT activities in cancer fibroblast cells. Importantly, zinc supplementation can diminish these activities, suggesting a protective role against the damaging effects of EMF exposure.