Abstract

Study Overview

This study examines the impact of 50 Hz extremely low frequency magnetic fields (ELF-MFs) on breast cancer cells, exploring both potential therapeutic and harmful effects.

Background

• Investigation into the response of breast cancer cells to ELF-MF exposure.
• Varied biological responses have been documented, highlighting the complex impact of ELF-MFs.

Methods and Results

• Cell lines used: MDA-MB-231, MCF-7 (cancerous), and MCF-10A (non-cancerous).
• Exposure settings: 50 Hz ELF-MF at 0.1 mT and 1.0 mT flux densities.
• Observations made 96 hours post-exposure.
• Short-term exposure led to increased cell viability, while prolonged exposure decreased viability and proliferation across all tested cell lines.
• Important changes in mitochondrial function and reactive oxygen species production were noted, implicating mitochondrial targeting by ELF-MF.

Conclusions

The study concludes that ELF-MF exposure can significantly affect the viability of breast cells, with effects varying based on exposure duration and strength. These findings underline the need for careful consideration of ELF-MF exposure levels in medical and occupational settings.