Abstract

Study Summary on Electromagnetic Field Exposure and Breast Cancer Cell Viability

Overview

The research explores the impact of exposure to extremely low frequency magnetic fields (ELF-MF), particularly a 50 Hz magnetic field, on breast cancer cell lines (MDA-MB-231 and MCF-7) and a non-tumorigenic breast cell line (MCF-10A).

Methodology & Findings

• Cells were exposed to 50 Hz ELF-MF at 0.1 mT and 1.0 mT flux densities.
• Viability and proliferation were assessed 96 hours post-exposure.
• Short-term exposures increased viability in cancer cells, whereas long/high exposures reduced cell viability and proliferation across all lines.
• Differential responses between cancerous and non-cancerous cells were noted, particularly in mitochondrial function and reactive oxygen species production, pinpointing mitochondria as potential ELF-MF targets.

Conclusion

Cell viability in breast cancer and non-cancerous cells is notably affected by ELF-MF, with effects observable after 96 hours. These changes are dependent on the duration and intensity of the exposure, suggesting significant implications for environmental health guidelines.