Effects of Long-Term Exposure of Intermediate Frequency Magnetic Fields (20 kHz, 360 µT) on the Development, Pathological Findings, and Behavior of Female Mice

Abstract

Overview

The study examines the effects of long-term exposure to intermediate frequency magnetic fields, specifically 20 kHz at 360 µT, on female mice. The focus is on developmental, pathological, and behavioral aspects under continuous exposure.

Findings

• Exposure started at 3 months of age with magnetic fields or a sham condition, continuing 24 hours a day.
• Body mass and survival rates showed no adverse differences. No significant changes were found in tumor incidence rates among the exposed and control groups.
• Behavioral tests indicated significant effects in Rotarod performance, suggesting potentially enhanced alertness or stress in exposed mice.
• Pathologically, the presence of neoplastic lesions was examined, and while findings were present, exposure to magnetic fields did not significantly escalate the risk.

Conclusion

Though the study revealed some variations in behavior suggesting behavioral changes, there were no significant findings related to growth and tumor development. Hence, chronic exposure to specified magnetic fields may not pose a severe health risk but warrants further investigation, particularly considering the observed behavioral changes. The study also highlights the need for extended analysis and inclusive research to confirm these findings across genders and longer periods.

Note: Exposed mice displayed a total of 17 pathological findings compared to 11 in the control group, which suggests a potential underreported risk in pathological alterations.