Abstract

Abstract Summary

Overview

The research aimed to investigate the impact of extremely low frequency electromagnetic fields (ELF-EMF) on energy metabolism and oxidative stress in the nematode Caenorhabditis elegans.

Findings

• Exposure Details: Experimental subjects were exposed to 50 Hz, 3 mT ELF-EMF during three stages of adulthood: young adult, egg-laying, and peak egg-laying stages.
• Energy Metabolism: Notable increases in ATP levels and mitochondrial ATP synthase activity were observed.
• Oxidative Stress Measurement: In the young adult stage, significant rises in ROS (reactive oxygen species) were noted alongside upregulated total antioxidant capacity (TAC), despite a decreased ROS-TAC score, which indicates oxidative stress.
• No remarkable changes in ROS level and TAC were noted in later adult stages (egg-laying and peak egg-laying).

Conclusion

The study concludes that ELF-EMF exposures are potent enough to enhance energy metabolism and induce significant oxidative stress, particularly marked by changes in ATP production and ROS levels in young adult C. elegans.