5G Electromagnetic Radiation Attenuates Skin Melanogenesis In Vitro by Suppressing ROS Generation

Authors: Kim K, Lee YS, Kim N, Choi H-D, Lim K-M

Year: 2022

Category: Dermatology

Journal: Antioxidants

DOI: 10.3390/antiox11081449

URL: https://www.mdpi.com/2076-3921/11/8/1449

Abstract

Overview

With the rise of 5G technology, the effects of 5G electromagnetic radiation (EMR) on human health have garnered substantial public attention. This study focuses on the specific impact of 28 GHz 5G EMR on skin pigmentation.

Findings

  • Experimentation with murine melanoma cells (B16F10) and a 3D pigmented human epidermis model (Melanoderm™) shows that 5G EMR can reduce skin pigmentation.
  • 5G EMR exposure was performed at 10 W/m2 for 4 hours daily over 16 days, which resulted in significant attenuation of melanin synthesis induced by α-MSH.
  • Detailed analysis confirmed the reduction in dendritic formation and suppression of melanogenic enzymes including tyrosinase, TRP-1, and TRP-2 due to 5G exposure.
  • Significantly, the study illuminates that 5G EMR reduces Reactive Oxygen Species (ROS) production, a critical component for melanin synthesis, thus indicating potential broader biological effects of 5G EMR on human health.

Conclusion

The findings reveal the potential public health implications of 5G technology, demonstrating that beyond facilitating communication, it might also influence biological functions with its ability to suppress critical cellular processes such as ROS generation and melanin synthesis in skin cells. This may represent a health risk that needs further examination in human studies.

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