The Effect of Electromagnetic Field on Decreasing and Increasing of the Growth and Proliferation Rate of Dermal Fibroblast Cell

Authors: Mehran Naghibzadeh, Seifollah Gholampour, Majid Naghibzadeh, Fatemeh Sadeghian-Nodoushan, Habib Nikukar

Year: 2020 Jun 11

Category: Dermatology

Journal: Dermatol Ther

DOI: 10.1111/dth.13803

URL: https://pubmed.ncbi.nlm.nih.gov/32526050/

Abstract

Overview

Maintaining the health of dermal fibroblast cells and controlling their growth and proliferation is crucial for the integrity of skin tissues. This study investigates the effects of electromagnetic fields (EMF) on these cells under various conditions.

Methodology

The research included three control and three experimental specimens, differing in EMF exposure duration and intensity:

  • Decreased intensity from 2 mT to 1 mT over 24, 48, and 72 hours resulted in increased cell proliferation rates by 60.3%, 144.9%, and 90.1%, respectively.
  • Increased intensity from 3 mT to 4 mT for durations of 48 and 72 hours saw decreases in proliferation rates by 6.8% and 86.7%, respectively.

Conclusion

The findings suggest optimizing conditions for wound restoration and skin lesion treatment through specific adjustments to EMF exposure intensity and duration. The study proposes that decreasing the exposure intensity from 2 mT to 0.5 mT and increasing EMF exposure time from 24 hours to 72 hours can non-invasively aid in skin restoration. Conversely, increasing the intensity from 3 mT to 5 mT and the exposure time from 48 to 72 hours could enhance non-invasive treatment methods for skin cancers.

electromagnetic fields dermal fibroblast skin health cell proliferation non-invasive treatment
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