Evaluation of Inflammation by Cytokine Production Following Combined Exposure to Ultraviolet and Radiofrequency Radiation of Mobile Phones on 3D Reconstructed Human Skin In Vitro
Abstract
Abstract Summary:
Overview
The study investigates the simultaneous effects of ultraviolet (UV) and radiofrequency (RF) radiation, both emitted by mobile phones, on human skin under controlled laboratory conditions.
Findings
- RF radiation from mobile devices has a high specific absorption rate, indicating significant penetration and potential effects on the skin.
- Solar UV radiation is known for causing multiple skin damages, prompting an examination of additional risks posed by mobile phone radiation.
- Experiments involved the application of 1950 MHz RF exposures from 3G mobile systems, either before or after UV irradiation, to evaluate potential cooperative or protective effects.
- No significant changes in inflammatory cytokines were observed with RF alone or when combined with UV radiation.
- A decrease in MMP-1 enzyme concentration was seen when RF exposure preceded UV exposure, though this was statistically nonsignificant.
Conclusion
Findings emphasize the need for further research on the impact of combined RF and UV exposure, especially considering the upcoming widespread use of 5G technologies. While RF exposure did not increase UV-induced skin damage, it altered certain inflammatory processes.