Metabolic, Apoptotic and Fibro-Inflammatory Profiles of the Heart Exposed to Environmental Electromagnetic Fields

Authors: Savchenko L, Martinelli I, Marsal D, Batkivska O, Zhdan V, Kaidashev I, Pizzinat N, Boal F, Tronchere H, Tao J, Kunduzova O

Year: 2023 Jul 20

Category: Molecular Biology

Journal: Int J Mol Sci

DOI: 10.3390/ijms241411709

URL: https://www.mdpi.com/1422-0067/24/14/11709

Abstract

Overview

Environmental stress can disturb the integrative functioning of the cardiovascular system and trigger adaptive and/or maladaptive cellular responses. The increasing use of mobile communications raises concerns about the effects of 900 MHz electromagnetic fields (EMFs) on cardiovascular health.

Findings

  • Exposure to 915 MHz EMF was investigated in a mouse model over 14 days.
  • Analysis included cardiac metabolic, antioxidative, apoptotic, and fibro-inflammatory profiles.
  • No significant changes were observed in oxidative phosphorylation or expression of myocardial fibro-inflammatory cytokines, antioxidant enzymes, and apoptosis markers.
  • The structural integrity of the cardiac tissues remained preserved.

Conclusion

This study suggests that the apoptotic, antioxidant, metabolic, and fibro-inflammatory profiles of the heart remained stable under EMF exposure in the analyzed mice, indicating no immediate risk to cardiovascular health from EMFs as per the parameters assessed.

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