Pre and postnatal exposure to 900 MHz electromagnetic fields induce inflammation and oxidative stress, and alter renin-angiotensin system components

Abstract

Overview

This study explores the impact of 900 MHz electromagnetic field (EMF) exposure on the brain and kidney tissues of both male and female rats, focusing on prenatally and/or postnatally exposed groups. The increasing use of mobile phones and the GSM 900 system underlines the relevance of understanding such effects.

Main Methods

• Study Subjects: Male and female Wistar albino offspring.
• Experimental Design: Divided into four groups - control, prenatal exposure, postnatal exposure, and prenatal + postnatal exposure to 900 MHz EMF.
• Duration: 1 hour/day exposure; 23 days during pregnancy and 40 days postnatally.

Findings

In comparison to control groups, significant findings include:

• Increased levels of pro-inflammatory markers (IL-2, IL-6, TNF-α) and oxidative stress markers.
• Decreased total antioxidant status.
• Enhanced expression of renin-angiotensin system components.

These changes were observed in both male and female tissues, although there were some sex-specific differences.

Conclusion

The study strongly indicates that exposure to 900 MHz EMF can lead to activation of the renin-angiotensin system in brain and kidney tissues, potentially linked to increased inflammation and oxidative stress. This suggests significant health risks associated with EMF exposure.