Does Microwave Exposure at Different Doses in the Pre/Postnatal Period Affect Growing Rat Bone Development?
Abstract
Effects of Microwave Exposure on Rat Bone Development
Overview: This study investigates the impact of 2.45 GHz continuous wave (CW) microwave (MW) radiation exposure during the pre and postnatal periods on rat bone development using biochemical and histological methods.
Methodology: Six groups of growing male rats, born from pregnant rats exposed to various low-level electromagnetic fields (EMF), were studied. Daily one-hour MW exposures at 2.45 GHz were conducted.
- Control Group: No exposure was given to this group.
- Experimental Groups: Exposed to different EMF levels.
Findings: There were no notable changes in biochemical markers such as RANK between the control and experimental groups. However, significant increases in sRANKL and Osteoprotegerin (OPG) were observed at 10 V/m and 15 V/m EMF exposures, suggesting potential bone development effects at these intensities. Histological analysis supported these findings.
Conclusion: The study suggests that exposure to EMF at specific intensities during critical developmental periods may influence bone development in rats. This is a pioneering study exploring these particular parameters.