Effects of Exposure to Radiofrequency at 2.45 GHz on Structural Changes Associated with Lipid Peroxidation in Prepubertal Rat Testicular Tissue

Authors: Karadayı A, Ünal N, Gülbahçe ME, Engiz B, Akkoca A, Varol S

Year: 2023

Category: Radiology

Journal: European Journal of Therapeutics

DOI: 10.58600/eurjther1875

URL: https://www.researchgate.net/publication/376283748_Effects_of_Exposure_to_Radiofrequency_at_245_GHz_on_Structural_Changes_Associated_with_Lipid_Peroxidation_in_Prepubertal_Rat_Testicular_Tissue

Abstract

Overview

The study explores the impact of non-ionizing electromagnetic radiation (EMR), emitted from everyday electronic devices, on biological systems, particularly focusing on testicular tissue in rats.

Objective

The primary objective was to assess the levels of lipid peroxidation through histological evaluation in the testicular tissue of prepubertal male rats exposed to various intensities of electromagnetic radiation within the 2.45 GHz radiofrequency spectrum.

Methods

  • The study included six subdivisions: a sham control group and groups exposed to different electric field strengths (0.6 V/m, 1.9 V/m, 5 V/m, 10 V/m, 15 V/m).
  • Exposure occurred daily for 1 hour starting immediately after fertilization and continued for 45 days post-birth.

Findings

Exposure to 2.45 GHz radiofrequency led to:

  • Increase in malondialdehyde (MDA) levels, indicating elevated oxidative stress.
  • Decrease in glutathione (GSH) levels, reflecting reduced antioxidant capacity.
  • Notable histological changes in the testicular tissue when compared to the control group.

Conclusion

The study concludes that significant histopathological and oxidative changes occur in testicular tissue of Wistar rats exposed to high electric fields, underscoring potential health implications.

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