Radiofrequency Fields and Calcium Movements Into and Out of Cells

Abstract

Overview

The exponential increase in 5G telecommunications has instigated important discussions on the potential "non-thermal" detrimental impacts of radiofrequency (RF) radiation on biological systems.

Findings

• The study revisits the hypothesis that low-level RF radiation could influence calcium dynamics, a topic of scrutiny for nearly half a century.
• Particular emphasis is given to the sensitivity of voltage-gated calcium channels (VGCCs) to RF fields.
• It addresses the coupling of RF modulations to the mechanisms controlling VGCCs, alongside a retrospective review of related studies over the past five decades.

Conclusion

Contrary to concerns, it appears that RF radiation, even when influenced by the ICNIRP guidelines, does not substantively impact the transport of Ca2+ ions into or out of cells. Moreover, no biological mechanisms have so far been definitively proven for the detection and rectification of these effects at extremely low frequencies.