The effect of exposure to radiofrequency fields on cancer risk in the general and working population: A protocol for a systematic review of human observational studies

Authors: Susanna Lagorio, Maria Blettner, Dan Baaken, Maria Feychting, Ken Karipidis, Tom Loney, Nicola Orsini, Martin Röösli, Marilia Silva Paulo, Mark Elwood

Year: 2021 Aug 22

Category: Epidemiology

Journal: Environ Int

Institution: World Health Organization

DOI: 10.1016/j.envint.2021.106828

URL: https://pubmed.ncbi.nlm.nih.gov/34433115/

Abstract

Overview

The World Health Organization (WHO) is actively investigating the potential health impacts of radiofrequency electromagnetic fields (RF-EMF) on both the general and working population. This systematic review is designed to synthesize existing human observational studies to better understand the cancer hazards associated with RF-EMF exposure.

Objective

The review aims to evaluate the quality and strength of the evidence linking RF-EMF exposure to the risk of developing cancerous neoplasms.

Eligibility Criteria

  • Types of exposure: Near-field, head-localized, and far-field whole body
  • Specific focus on certain neoplasms including brain, meninges, and salivary gland tumors

Methodology

Relevant studies will be extracted from Medline, Embase, and EMF-Portal. A customized OHAT risk of bias tool will assess the validity of these studies.

Data synthesis will be carried out separately for different tumors and exposures, considering both adult and child subjects. Depending on the data, analysis could range from quantitative meta-analysis to narrative synthesis.

Evidence Assessment

Evidence reliability will be determined using the GRADE approach, ensuring a thorough review and robust conclusions are made about the carcinogenic potential of RF-EMF.

Funding and Support

This study is backed by the WHO, with additional support from various international health agencies.

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