Effects of Exposure to Radiofrequency at 2.45 GHz on Structural Changes Associated with Lipid Peroxidation in Prepubertal Rat Testicular Tissue

Abstract

Overview

The increasing use of electronic devices has escalated exposure to non-ionizing electromagnetic radiation (EMR), triggering oxidative damage in biological systems, notably influencing the reproductive capability of exposed tissues.

Objective

• To investigate the levels of lipid peroxidation via histological analysis in the testicular tissue of prepubertal rats under varying intensities of electromagnetic exposure at 2.45 GHz frequency.

Methods

The study involved an experimental group with six subdivisions: a control group and subgroups exposed to electric field strengths of 0.6 V/m, 1.9 V/m, 5 V/m, 10 V/m, and 15 V/m. These subgroups, excluding the control, underwent daily exposure to 2.45 GHz for 1 hour from fertilization, continuing post-birth for 45 days.

Findings

• Elevated malondialdehyde (MDA) levels indicate increased lipid peroxidation.
• A decrease in glutathione (GSH) levels showing diminished antioxidative defense.
• Histological examinations revealed significant structural changes among rats exposed to higher intensities of EMR.

Conclusion

Exposure to 15 V/m electric field intensity of microwave radiation results in critical histopathological and oxidative changes in testicular tissues, posing potential health risks which might extend to human health impacts.