Abstract

Overview

Long-term evolution (LTE) radiofrequency electromagnetic field (RF-EMF) is extensively utilized in communication technology, raising concerns about its effects on biological systems. The study builds upon previous findings that demonstrated potential changes in cell behavior under continuous RF-EMF exposure.

Findings

• Enhancements were made to the 1.7 GHz RF-EMF cell exposure system to stabilize exposure power, which maintained target power levels within a 3% deviation and a constant temperature during a 72-hour exposure period.
• The study tested the exposure effect on various human and rat cell lines, focusing on parameters like cell proliferation, DNA damage, and cell cycle perturbation, with and without thermal control.
• Results indicated that the RF-EMF exposure, when thermally controlled, did not significantly alter the proliferation or induce DNA damage compared to unexposed controls.
• Cellular effects noted in conditions of uncontrolled thermal increase suggest that physiological changes might be primarily due to temperature alterations rather than direct RF-EMF exposure.

Conclusion

The refined 1.7 GHz LTE RF-EMF exposure system, capable of maintaining consistent power and controlled thermal conditions, indicates no direct cellular mutation or proliferation effect under the study conditions. This reinforces the hypothesis that observed cellular changes in previous studies may largely stem from thermal factors rather than RF-EMF itself.