Abstract

Overview

This research examines the cellular implications of 1950 MHz, long-term evolution (LTE) radiofrequency signals, either alone or combined with mitomycin-C (MMC), a known cytotoxic agent, on Chinese hamster lung fibroblast (V79) cells.

Experimental Setup

• Cells were exposed in a waveguide-based system to specific absorption rates (SAR) of 0.3 and 1.25 W/kg.
• Conditions of electromagnetic and environmental parameters were strictly controlled.

Findings

• No significant differences were found in chromosomal damage, oxidative stress, and cell cycle progression between radiofrequency exposed and control groups under most conditions.
• However, pre-exposure to radiofrequency at 1.25 W/kg significantly reduced MMC-induced chromosomal damage.
• Additionally, MMC-induced oxidative stress was decreased at both SAR levels tested, but cell proliferation and cycle progression remained unchanged.

Conclusion

The study finds no direct harmful effects from 1950 MHz LTE signal exposure. Interestingly, it suggests that radiofrequency exposure could have a protective effect against further toxic exposures depending on the SAR level and signal modulation endured.