Cellular Response to ELF-MF and Heat: Evidence for a Common Involvement of Heat Shock Proteins?
Abstract
Overview
This review examines how magnetic fields in the extremely low frequency range (ELF-MF), regarded as stressors, interact with cellular mechanisms similar to those engaged during heat exposure, focusing especially on the role of heat shock proteins (HSPs).
Findings
- ELF-MF exposure, even below limits set by exposure guidelines, acts as a stressor in various biological systems.
- Both ELF-MF and heat exposures result in the activation of heat shock proteins, key elements in cellular protection and stress response.
- The presence of MF can potentiate the response to heat exposure, leading to increased expression of HSPs and potentially beneficial effects under certain conditions.
Conclusion
The review suggests the co-stressor effect of ELF-MF and heat could enhance thermotolerance in cell cultures and organisms, representing a significant intersection of cellular responses to environmental and physiological elements.