Cellular Response to ELF-MF and Heat: Evidence for a Common Involvement of Heat Shock Proteins?

Authors: Zeni O, Simkó M, Rosaria Scarfi M, Mattsson MO

Year: 18 October 2017

Category: Public Health

Journal: Public Health

DOI: 10.3389/fpubh.2017.00280

URL: https://www.frontiersin.org/articles/10.3389/fpubh.2017.00280/full

Abstract

Overview

This review examines how magnetic fields in the extremely low frequency range (ELF-MF), regarded as stressors, interact with cellular mechanisms similar to those engaged during heat exposure, focusing especially on the role of heat shock proteins (HSPs).

Findings

  • ELF-MF exposure, even below limits set by exposure guidelines, acts as a stressor in various biological systems.
  • Both ELF-MF and heat exposures result in the activation of heat shock proteins, key elements in cellular protection and stress response.
  • The presence of MF can potentiate the response to heat exposure, leading to increased expression of HSPs and potentially beneficial effects under certain conditions.

Conclusion

The review suggests the co-stressor effect of ELF-MF and heat could enhance thermotolerance in cell cultures and organisms, representing a significant intersection of cellular responses to environmental and physiological elements.

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