The effect of exposure to radiofrequency LTE signal and coexposure to mitomycin-C in Chinese hamster lung fibroblast V79 cells

Authors: Sannino A, Romeo S, Scarfì MR, Pinchera D, Schettino F, Alonzo M, Allocca M, Zeni O

Year: 2023 Jul 26

Category: Bioelectromagnetics

Journal: Bioelectromagnetics

DOI: 10.1002/bem.22478

URL: https://pubmed.ncbi.nlm.nih.gov/37493434/

Abstract

Overview

This study explores the cellular impacts from exposure to a 1950 MHz LTE (Long-Term Evolution) radiofrequency signal, administered alone or alongside mitomycin-C (MMC), a known cytotoxic agent, on Chinese hamster lung fibroblast V79 cells.

Methodology

  • Exposure was conducted in a waveguide-based system with strict control over electromagnetic and environmental conditions.
  • Specific absorption rate (SAR) values were set at 0.3 and 1.25 W/kg.

Findings

Key observations noted in the study include:

  • No observable differences between radiofrequency-exposed samples and sham-controls under all tested conditions.
  • Emergence of protective effects against MMC-induced damage under specific conditions of pre-exposure.

Conclusion

Findings suggest that exposure to a 1950 MHz LTE signal alone shows no direct cellular effects. However, conditions of pre-exposure to the LTE frequency may provide cellular protection against subsequent cytotoxic treatments.

radiofrequency cellular effects LTE signal oxidative stress chromosomal damage
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