Effects of Radiofrequency Exposure and Co-Exposure on Human Lymphocytes: Influence of Signal Modulation and Bandwidth

Authors: Romeo S, Sannino A, Zeni O, Angrisani L, Mass R, Scarfi MR

Year: May 20, 2019

Category: Electromagnetics, RF and Microwaves in Medicine and Biology

Journal: IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology

Institution: IEEE

DOI: 10.1109/JERM.2019.2918023

URL: https://ieeexplore.ieee.org/document/8718560

Abstract

Abstract Overview

The research focuses on the effects of Radiofrequency (RF) and other agents on human lymphocytes, specifically exploring how signal modulation and bandwidth influence DNA damage.

Methodology & Key Findings

  • Blood cultures from healthy donors were exposed to a 1950 MHz frequency with different RF signals, namely CW, WCDMA, and AWGN.
  • Specific Absorption Rate (SAR) values tested were 0.15, 0.3, 0.6, 1.25 W/kg.
  • RF exposure alone did not induce DNA damage; however, co-exposure with mitomycin-C (MMC) showed modulation-dependent effects.
  • A protective effect was observed in certain conditions, correlating with specific modulations and bandwidths.

Implications & Conclusion

The study reveals that RF electromagnetic fields could potentially protect mammalian cells from genotoxic insults. This protective effect is dependent on the modulation and bandwidth of the signal used, suggesting a pathway for innovative clinical applications of RF fields.

If these findings are validated in vivo, they could pave the way for new therapeutic methods that utilize RF fields to shield cells from harmful side effects of treatments.

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