Adverse and beneficial effects in Chinese hamster lung fibroblast cells following radiofrequency exposure
Abstract
Overview
This study investigates the impact of radiofrequency (RF) exposure on Chinese hamster lung fibroblast cell line (V79), focusing on genotoxic and cytotoxic effects under various specific absorption rate (SAR) conditions.
Findings
- The investigation was conducted using a 1950 MHz, Universal Mobile Telecommunication System signal over a 20-hour exposure period.
- Exposures at lower SAR values (0.15 and 0.3 W/kg) showed statistically significant increases in micronucleus (MN) frequency, indicating genotoxic effects.
- No significant effects were observed at higher SAR values (0.6 and 1.25 W/kg).
- A protective effect was noted at a SAR of 1.25 W/kg against chemical mutagen mitomycin-C, suggesting an adaptive response in the cell cultures.
Conclusion
This study highlights the dual nature of RF exposure effects on cellular structures, demonstrating both adverse and potentially beneficial outcomes based on the applied experimental conditions.