Exposure to 10 Hz Pulsed Magnetic Fields Do Not Induce Cellular Senescence in Human Fetal Lung Fibroblasts

Authors: Sun Chuan, Huang Zheng, Qin Houbing, Zhang Jing, Wang Sanying, Xu Xiaogang, Ying Shibo, Mao Genxiang

Year: 2021

Category: Public Health

Journal: Frontiers in Public Health

DOI: 10.3389/fpubh.2021.761069

URL: https://www.frontiersin.org/article/10.3389/fpubh.2021.761069

Abstract

Overview

Rapid population aging has led to a global burden of late-life diseases. Aging, a key risk factor for many age-related diseases, is influenced by both genetic and external factors, among which electromagnetic fields (EMFs) play a significant role.

Findings

  • Cells are the fundamental units of organs and tissues in the body, and cellular senescence is vital in the aging process.
  • The study explores the effects of 10 Hz pulsed magnetic fields on cellular senescence in the 2BS cell line derived from human fetal lung fibroblasts.
  • Intermittent exposure (1 day on/1 day off) to 10 Hz pulsed magnetic fields at 1.0 mT for two weeks was shown to induce DNA damage, although no significant cellular senescence phenotypes were observed in 2BS cells.

Conclusion

The inconsistent results highlight the necessity for further investigation into the impact of EMFs on aging and cellular processes.

EMF cellular senescence aging human fetal lung fibroblasts pulsed magnetic fields DNA damage
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