Abstract

Overview

The purpose of this study was to explore the effects of microwave radiation on cardiac health in rats, with a particular focus on the role of heat shock protein 72 (Hsp72).

Findings

• Measurement of rats' rectal temperature before and after radiation exposure showed significant increases post-radiation.
• Changes in electrocardiogram patterns were noted, along with a decrease in ion concentrations and alterations in myocardial enzyme activities.
• Increased levels of myocardial injury markers and hormones were detected using ELISA and radioimmunoassay, respectively.
• Detailed observations of myocardial tissue structure via optical and transmission electron microscopy revealed damage.
• Significant increase in Hsp72 expression was documented, indicating its role in response to stress induced by microwave radiation.

Conclusion

This study highlights the damaging effects of S-wave microwave radiation at 30 mW/cm2 for 35 minutes on cardiac functionality, driven by both thermal and nonthermal mechanisms. It underscores the critical nature of understanding microwave radiation's impact on cardiac health, especially in relation to Hsp72's response in such stress conditions.